Better Outcomes Are Needed
Dialysis is the primary lifeline for patients with end-stage renal disease, but dialysis access sites are prone to failure, reducing the quality and length of life for patients.
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People worldwide suffer from chronic kidney disease Lv JC, Zhang LX. Prevalence and Disease Burden of Chronic Kidney Disease. Adv Exp Med Biol. 2019;1165:3-15. doi: 10.1007/978-981-13-8871-2_1.
End-stage renal disease patients on hemodialysis in the US United States Renal Data System. 2020 USRDS Annual Data Report: Epidemiology of kidney disease in the United States. End Stage Renal Disease, Chapter 3: Vascular Access. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2020.
Failure rate of dialysis access sites in the first year United States Renal Data System. 2018 USRDS Annual Data Report: Epidemiology of kidney disease in the United States. Chapter 3: Vascular Access. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2018. Al-Jaishi AA, Oliver MJ, Thomas SM, Lok CE, Zhang JC, Garg AX, Kosa SD, Quinn RR, Moist LM. Patency rates of the arteriovenous fistula for hemodialysis: a systematic review and meta-analysis. Am J Kidney Dis. 2014 Mar;63(3):464-78. doi: 10.1053/j.ajkd.2013.08.023. Epub 2013 Oct 30.
Annual Medicare costs due to access site failures Thamer M, Lee TC, Wasse H, Glickman MH, Qian J, Gottlieb D, Toner S, Pflederer TA. Medicare Costs Associated With Arteriovenous Fistulas Among US Hemodialysis Patients. Am J Kidney Dis. 2018 Jul;72(1):10-18. doi: 10.1053/j.ajkd.2018.01.034. Epub 2018 Mar 28.